二郎神 发表于 2018-3-21 10:14:01

罕见柱状细胞型PTC伴β-hCG分泌

  作者:谷海燕 刘志艳

  谷海燕医生2017年甲状腺高峰论坛汇报一罕见柱状细胞型甲状腺乳头状癌伴β-hCG分泌,随访三年余无复发,整理后除夕夜得以发表,共勉之。
  Abstract
  Columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is an unusual neoplasm, the clinical behavior of which mainly depends on the encapsulation or infiltration. Patients with extensive extrathyroidal extension usually have an aggressive biological behavior. This study confirmed that beta-human chorionic gonadotropin (β-hCG) secreting invasive CCV-PTC has good prognosis comparing with a cohort of follicular cell differentiated thyroid carcinoma. On the contrary, positive immunoreaction with β-hCG was proved in three anaplastic thyroid carcinoma patients showing aggressive clinical courses. The clinicopathologic characteristics of CCV-PTC and the paraneoplastic syndromes in follicular cell differentiated thyroid carcinoma were further summarized using literature review.

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