去分化脂肪肉瘤？讨论病例【91360.软组织313】

刘伟

一公里生命
病例分享第170例
️ What is your Dx of this paratesticular lesion?

️ What molecular alteration would you expect to find in this lesion?


邓天朝
PHAT
去分化脂肉

一公里生命
Dedifferentiated liposarcoma. Clin: Rare; most common paratesticular sarcoma in adults. Histo: Well-diff = adipose w/fibrous bands; large atypical cells w/hyperchromasia.
Dediff: HG sarcoma or heterologous sarcoma.
Molec: Amp 12q13-15️ ^MDM2, CDK4, HMGA2


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