罕见柱状细胞型PTC伴β-hCG分泌

二郎神

　　作者：谷海燕 刘志艳

　　谷海燕医生2017年甲状腺高峰论坛汇报一罕见柱状细胞型甲状腺乳头状癌伴β-hCG分泌，随访三年余无复发，整理后除夕夜得以发表，共勉之。
　　Abstract
　　Columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is an unusual neoplasm, the clinical behavior of which mainly depends on the encapsulation or infiltration. Patients with extensive extrathyroidal extension usually have an aggressive biological behavior. This study confirmed that beta-human chorionic gonadotropin (β-hCG) secreting invasive CCV-PTC has good prognosis comparing with a cohort of follicular cell differentiated thyroid carcinoma. On the contrary, positive immunoreaction with β-hCG was proved in three anaplastic thyroid carcinoma patients showing aggressive clinical courses. The clinicopathologic characteristics of CCV-PTC and the paraneoplastic syndromes in follicular cell differentiated thyroid carcinoma were further summarized using literature review.