骨：小细胞骨肉瘤？讨论病例【91360.软组织544】

刘伟

一公里生命
病例(形态)分享第344例
骨

KK
骨肉瘤，普通型。图不太清晰

伊人一方
@kk 顶

岁月静好
+1

一公里生命
SMALL CELL OSTEOSARCOMA: rare variant of OS with round/ovoid/spindle cells and production of osteoid (often focal/wispy). SATB2 +, CD99 - or focal. DDx: Ewing sarcoma; however, more pleomorphic and spindled than ES.  “Small cell” is subjective and somewhat arbitrary.

KK
这个亚型原作者给的不太准确。小细胞型骨肉瘤的细胞和尤文很相似，在穿刺标本时，和尤文仅从形态学上有时候很难区别，必要找到肿瘤性成骨，有时候需要FISH协助诊断。

一公里生命
Some chicken wire calcification.
Small cell is one of the most subjective and arbitrary descriptions in pathology ever.

注：病例来自网络，版权归原作者仅供学习